Reimagining Antibody Discovery and Sequencing

Digital Proteomics Featured Products and Services

At Digital Proteomics our inspiration comes from the lab, but our approaches use the latest computational and machine learning methods.

Valens^TM
Antibody protein sequencing

Need to sequence an antibody but have lost the source cells? Valens can perform de novo antibody sequencing to determine the full-length heavy and light chain sequences of your antibody from any species and any isotype.

Alicanto^®
Single domain antibody discovery

Discover diverse, natural single domain antibodies using Alicanto^®. Our proprietary platform effectively mines the immune response without cloning or panning.

Alicanto^®
Rabbit monoclonal antibody discovery

Custom rabbit monoclonal antibody discovery for high affinity, assay-ready antibodies. Our proprietary platform, Alicanto^®, enriches for a diverse, high affinity collection of monoclonal antibodies.

Reptor^TM
Next-gen sequencing of B cells

An all-in-one B-cell receptor sequencing and analysis service, delivered on the cloud. We can sequence hybridomas, phagemids, or B cells to meet the needs of your antibody discovery, library characterization, or basic research goals.

Reptor^TM
Hybridoma sequencing

High-throughput, accurate sequencing of hybridomas by next-generation sequencing. Our Reptor platform identifies major and minor clones present in your hybridomas.

Alicanto^®
Human antibody discovery

Discover monoclonal antibodies directly from patients. We can be your partner in human antibody repertoire analysis with our Alicanto^® platform for identifying antibodies directly from serum.

Quorum Cloud^®
Molecular networking software

Quorum Cloud^® is a cloud-backed software platform for discovery metabolomics using molecular networks constructed from mass spectrometry data.

Alicanto^®
Custom monoclonal antibody discovery

Discover better monoclonal antibodies from your species-of-interest, we can customize to your needs. Alicanto^® is our proprietary platform for custom antibody discovery without cloning or panning.

Antibody repertoire sequencing: Error correction

Sequencing errors: where do they come from? Immune repertoire sequencing (Rep-seq) allows us to deconvolute the population of antibody sequences that comprise an individual's B-cell response. While antibody repertoire diversity ...
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November 5, 2019

Llama VHH Discovery By Serum Proteomic Analysis

Llama VHH discovery from serum Camelids, such as llamas and alpacas, naturally produce both conventional antibodies and heavy-chain only antibodies (HCAbs)(1). The antigen-binding domain of the HCAb, called the VHH ...
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October 22, 2019

Isoleucine and Leucine determination in de novo antibody sequencing

Isoleucine and leucine determination De novo antibody sequencing by tandem mass spectrometry(MS/MS) uses the differences in mass of different amino acids to accurately determine the correct sequence. Distinguishing between isoleucine ...
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July 1, 2019

Vicugna vicugna grazing in the Atacama desert

Single-molecule Ig repertoire sequencing from Lama glama

In recent years, camelids have become more than hearty travel companions due to their unconventional adaptive immune systems. Conventional IgG antibodies are tetrameric molecules comprised of two heavy chains and ...
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May 22, 2019

Digital Proteomics is reimagining antibody discovery and sequencing