De novo antibody sequencing experience
- Have you lost your hybridoma?
- Is your hybridoma no longer producing?
- Is your hybridoma producing more than your desired antibody?
- Do you have a monoclonal antibody from a clinical sample, but no way to recover the source B cell?
Valens is a de novo antibody sequencing service that reconstructs the full amino acid sequence of both antibody chains using bioinformatics and mass spectrometry. We now offer this unique service in partnership with LakePharma, a leading protein engineering company.
For the past decade, we’ve been developing methods for sequencing monoclonal antibodies using proteomics. We wrote a blog post providing an overview of de novo antibody sequencing. For 100% sequence accuracy, antibody sequencing experience matters.
Resources and publications
Valens builds on over a decade of algorithm development including ideas invented at the University of California – San Diego Center for Computational Mass Spectrometry. For background on our methods check out these publications: